کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
3065582 | 1580485 | 2007 | 12 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Time course of tissue remodelling and electrophysiology in the rat sciatic nerve after spiral cuff electrode implantation
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کلمات کلیدی
موضوعات مرتبط
علوم زیستی و بیوفناوری
ایمنی شناسی و میکروب شناسی
ایمونولوژی
پیش نمایش صفحه اول مقاله
![عکس صفحه اول مقاله: Time course of tissue remodelling and electrophysiology in the rat sciatic nerve after spiral cuff electrode implantation Time course of tissue remodelling and electrophysiology in the rat sciatic nerve after spiral cuff electrode implantation](/preview/png/3065582.png)
چکیده انگلیسی
Implantation of nerve cuff electrodes induces inflammatory cell infiltration and loose connective tissue accumulation. Along with time, morphological changes evolve towards a thicker epi/perineurium as part of mechanisms that protect nerve functionality when a foreign body is wrapped around it. The rise in electrode impedance is linked to the nature of the epineurial tissue. Changes involve an increased expression of neuroprotective factors that is stronger in the endoneurium with axonal degeneration. Our data indicate that epineurial and endoneurial changes after electrode cuff implantation are part of axonal protection mechanisms. Their control is important to improve the yield of FES applications.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Journal of Neuroimmunology - Volume 185, Issues 1–2, April 2007, Pages 103–114
Journal: Journal of Neuroimmunology - Volume 185, Issues 1–2, April 2007, Pages 103–114
نویسندگان
Marie-Anne Thil, Dai Tran Duy, Ides M. Colin, Jean Delbeke,