کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
3065726 | 1580489 | 2006 | 5 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Increased serum levels of soluble CD14 indicate stable multiple sclerosis
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کلمات کلیدی
موضوعات مرتبط
علوم زیستی و بیوفناوری
ایمنی شناسی و میکروب شناسی
ایمونولوژی
پیش نمایش صفحه اول مقاله
![عکس صفحه اول مقاله: Increased serum levels of soluble CD14 indicate stable multiple sclerosis Increased serum levels of soluble CD14 indicate stable multiple sclerosis](/preview/png/3065726.png)
چکیده انگلیسی
The aim of this study was to evaluate a possible role of soluble CD14 (sCD14) in multiple sclerosis (MS). We found that sCD14 serum levels measured by ELISA were higher in MS patients compared to neurological and healthy controls. Within the MS group sCD14 levels were increased in relapsing–remitting and secondary progressive MS compared to primary progressive MS. Furthermore, sCD14 concentrations were increased during stable disease. An increased expression of sCD14 was also detected after treatment with interferon-beta. In summary, we report evidence that serum sCD14 levels are increased in MS and correlate inversely with disease activity in relapsing MS patients.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Journal of Neuroimmunology - Volume 181, Issues 1–2, December 2006, Pages 145–149
Journal: Journal of Neuroimmunology - Volume 181, Issues 1–2, December 2006, Pages 145–149
نویسندگان
Andreas Lutterotti, Bettina Kuenz, Viktoria Gredler, Michael Khalil, Rainer Ehling, Claudia Gneiss, Robert Egg, Florian Deisenhammer, Thomas Berger, Markus Reindl,