کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
3065739 | 1580486 | 2007 | 10 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Neurodegeneration in autoimmune demyelination: Recent mechanistic insights reveal novel therapeutic targets
دانلود مقاله + سفارش ترجمه
دانلود مقاله ISI انگلیسی
رایگان برای ایرانیان
موضوعات مرتبط
علوم زیستی و بیوفناوری
ایمنی شناسی و میکروب شناسی
ایمونولوژی
پیش نمایش صفحه اول مقاله
![عکس صفحه اول مقاله: Neurodegeneration in autoimmune demyelination: Recent mechanistic insights reveal novel therapeutic targets Neurodegeneration in autoimmune demyelination: Recent mechanistic insights reveal novel therapeutic targets](/preview/png/3065739.png)
چکیده انگلیسی
Multiple sclerosis (MS) is the most common chronic demyelinating disease of the central nervous system (CNS) and the major cause of neurological disability in young adults in Western countries. In spite of intensive research efforts, treatment options established to date do not sufficiently prevent the accumulation of tissue damage and clinical disability in patients with MS. We here describe recently identified molecules responsible for the inflammatory and the neurodegenerative processes in MS and its animal model, experimental autoimmune encephalomyelitis (EAE), and review new treatment options targeting both aspects of this disease.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Journal of Neuroimmunology - Volume 184, Issues 1–2, March 2007, Pages 17–26
Journal: Journal of Neuroimmunology - Volume 184, Issues 1–2, March 2007, Pages 17–26
نویسندگان
Orhan Aktas, Sonia Waiczies, Frauke Zipp,