کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
3073036 1188820 2008 9 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
MEG imaging of sensorimotor areas using inter-trial coherence in vibrotactile steady-state responses
موضوعات مرتبط
علوم زیستی و بیوفناوری علم عصب شناسی علوم اعصاب شناختی
پیش نمایش صفحه اول مقاله
MEG imaging of sensorimotor areas using inter-trial coherence in vibrotactile steady-state responses
چکیده انگلیسی

We utilized a novel analysis technique to identify brain areas that activate synchronously during the steady-state interval of responses to vibrotactile stimulation of the right index finger. The inter-trial coherence at the stimulation rate (23 Hz) was determined for whole-brain neural activity estimates based on a linearly-constrained minimum variance beamformer applied to the MEG data. Neural activity coherent with the stimulus occurred in the contralateral primary somatosensory cortex in all subjects, and matched well with equivalent dipole modeling of the same data. Subsets of subjects exhibited additional loci of strongly coherent activity in the contralateral primary motor cortex, posterior parietal cortex, and supplementary motor area, as well as in deeper brain structures above the brainstem. An activation delay of 7 ms from deep structures to cortical areas was estimated based on the mean phase at each coherent neural source within a single subject. This new approach – volumetric mapping of the statistical parameter of inter-trial coherence in steady-state oscillations – broadens the range of MEG beamformer applications specifically for identifying brain areas that are synchronized to repetitive stimuli.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: NeuroImage - Volume 42, Issue 1, 1 August 2008, Pages 323–331
نویسندگان
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