کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
3074224 1188864 2006 10 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Neuronal chronometry of target detection: Fusion of hemodynamic and event-related potential data
موضوعات مرتبط
علوم زیستی و بیوفناوری علم عصب شناسی علوم اعصاب شناختی
پیش نمایش صفحه اول مقاله
Neuronal chronometry of target detection: Fusion of hemodynamic and event-related potential data
چکیده انگلیسی

Event-related potential (ERP) studies of the brain's response to infrequent, target (oddball) stimuli elicit a sequence of physiological events, the most prominent and well studied being a complex, the P300 (or P3) peaking approximately 300 ms post-stimulus for simple stimuli and slightly later for more complex stimuli. Localization of the neural generators of the human oddball response remains challenging due to the lack of a single imaging technique with good spatial and temporal resolution. Here, we use independent component analyses to fuse ERP and fMRI modalities in order to examine the dynamics of the auditory oddball response with high spatiotemporal resolution across the entire brain. Initial activations in auditory and motor planning regions are followed by auditory association cortex and motor execution regions. The P3 response is associated with brainstem, temporal lobe, and medial frontal activity and finally a late temporal lobe “evaluative” response. We show that fusing imaging modalities with different advantages can provide new information about the brain.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: NeuroImage - Volume 30, Issue 2, 1 April 2006, Pages 544–553
نویسندگان
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