Xiyanping Injection in Treatment of Viral Pneumonia in Children: A Meta-analysis of Random Control Trials

ObjectiveTo evaluate the efficacy and safety of Xiyanping Injection in the treatment of viral pneumonia in children.MethodsWe searched several databases, including PubMed, CNKI, VIP and Wanfang Data (January— June, 2014). The references of all selected studies were also retrieved to collect the relevantly randomized controlled trials (RCTs) on Xiyanping Injection for viral pneumonia in children. Two authors screened the literatures in accordance with the inclusive criteria, extracted the data and assessed the methodological quality of the included studies. We used RevMan 5.2 software for meta-analysis.ResultsMeta-analysis on the 10 included RCTs showed that the effective rates of defervescing and vanishing of the rashes and cough in the Xiyanping Injection group were better than those in the Ribavirin Injection group. There was no significant difference between the two groups in the incidence of adverse drug reaction.ConclusionThe existing research indicated that Xiyanping Injection is a secure and efficient scheme for viral pneumonia in children. Because of the poor quality of present researches, these results should be verified by strictly-designed and large-scale sample RCTs.