کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
3101490 1191255 2008 6 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Determinants of folic acid use in early pregnancy in a multi-ethnic urban population in The Netherlands: The Generation R study
موضوعات مرتبط
علوم پزشکی و سلامت پزشکی و دندانپزشکی طب مکمل و جایگزین
پیش نمایش صفحه اول مقاله
Determinants of folic acid use in early pregnancy in a multi-ethnic urban population in The Netherlands: The Generation R study
چکیده انگلیسی

ObjectiveRecommendations on folic acid use to prevent neural tube defects have been launched in several countries. Adequate folic acid use seems to be low. This study assesses the prevalence of folic acid use and identifies its determinants.MethodsThe study was embedded in the Generation R Study Rotterdam, the Netherlands, a population-based prospective cohort study between 2002 and 2006. Complete information of 6940 women was available. Information on folic acid use and potential determinants was obtained by questionnaires and physical examination.ResultsOf all women 37% adequately used folic acid during the preconception period. Most important risk factors for inadequate use were unplanned pregnancy (OR 9.5, CI 7.2–12.4, p < 0.001), low educational level (OR 2.5, CI 1.8–3.6, p < 0.001) and non-western ethnicity, (OR 3.5, CI 2.9–4.3, p < 0.001). After stratification for ethnicity, unplanned pregnancy remained the most important risk factor for inadequate use. Other risk factors for inadequate use were younger age, single marital status, smoking, multiparity (all p < 0.001) and alcohol use (p < 0.05). In contrast, previous spontaneous abortion decreased the risk of inadequate folic acid use (p < 0.001).ConclusionAdequate preconception folic acid supplementation is still too low. Implementation of preconception programs and other public health strategies are strongly needed.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Preventive Medicine - Volume 47, Issue 4, October 2008, Pages 427–432
نویسندگان
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