کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
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3103693 | 1581703 | 2014 | 7 صفحه PDF | دانلود رایگان |
ObjectiveTo observe the effect of electroacupuncture (EA) on egg quality of polycystic ovarian syndrome (PCOS) patients, and to explore its mechanism.MethodsTwo hundred patients who received in vitro fertilization-embryo transfer (IVF-ET) were divided into an EA group (102 cases) and a control group (98 cases) according to random number table. All the patients in the two groups were given Diane-35 and gonadotropin-releasing hormone agonist (GnRH-a) for ovarian hyperstimulation. Besides, EA intervention was applied to Shènshù ( BL 23), Qìhăi ( GV 6), Zúsānl ( ST 36), Sānyīnjiāo ( SP 6), Nèiguān ( PC 6) and Zgōng ( EX-CAl), etc. in the EA group. Then egg quality, final outcome of pregnancy and levels of tumor necrosis factor-a (TNF-α) were compared between the two groups.Results(1) EA intervention significantly improved high quality embryo rate of PCOS patients (P<0.05), and clinical pregnancy rate was increased by 8.36%; (2) EA intervention significantly reduced the TNF-α levels of follicular fluid (13.61±15.46 vs 34.09±93.53, P<0.05); (3) TNF-α levels of serum and follicular fluid in the pregnancy group were lower than those of non-pregnancy group [pregnancy group: (53.91±63.32) pg/mL, (14.93±25.37) pg/mL, non-pregnancy group: (76.82±82.96) pg/mL, (25.04±35.79) pg/mL], and the differences were significant (both P<0.05).ConclusionEA improves egg quality of PCOS patients and increases the clinical pregnancy rate of IVF-ET, the mechanism may be related to TNF-α levels.
Journal: World Journal of Acupuncture - Moxibustion - Volume 24, Issue 3, 30 September 2014, Pages 9-15