کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
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3104690 | 1191660 | 2013 | 9 صفحه PDF | دانلود رایگان |
![عکس صفحه اول مقاله: Measurement of elasticity and transepidermal water loss rate of burn scars with the Dermalab® Measurement of elasticity and transepidermal water loss rate of burn scars with the Dermalab®](/preview/png/3104690.png)
This cross-sectional study investigated the reproducibility of repeated elasticity and transepidermal water loss (TEWL) measurements with the DermaLab® on 32 active burn scars and healthy skin. Intra- and inter-observer reproducibility was examined by means of intra-class correlation coefficients (ICC) and standard error of measurements (SEM). Results showed good ICC values and rather high SEM values for inter- and intra-observer reproducibility of elasticity measurements. For TEWL measurements, ICC values were good and SEM values were high for inter- and intra-observer reproducibility. There was a significant difference between the estimated mean elasticity values of normal skin and grafted scars and between normal skin and spontaneously healed scars (p ≤ 0.003). For the estimated mean TEWL values, there was a significant difference between normal skin and spontaneously healed scars (p = 0.036). A significant negative relation was reported between mean TEWL and time after burn (p = 0.008). In clinical trials it is necessary to interpret patient-specific changes in elasticity and TEWL with caution, since the SEMs of both modes are rather high. We therefore recommend the use of a mean of repeated measurements of elasticity and TEWL to decrease the SEM.
Journal: Burns - Volume 39, Issue 3, May 2013, Pages 420–428