کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
3105044 1191671 2013 9 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Colistin in burn intensive care: Back to the future?
موضوعات مرتبط
علوم پزشکی و سلامت پزشکی و دندانپزشکی مراقبت های ویژه و مراقبتهای ویژه پزشکی
پیش نمایش صفحه اول مقاله
Colistin in burn intensive care: Back to the future?
چکیده انگلیسی
Colistin is a venerable antibiotic whose fortunes have been revived by its excellent activity, the diminishing output of novel clinically effective antibiotics and the increasing importance of MDR infection in burn surgery, both in the civilian and military arenas. This review synthesizes current evidence on the usage of colistin in burn surgery including the structure-activity relationship; dosing, pharmacokinetics/pharmacodynamic (PK/PD), analytic methods, resistance and current research efforts into the redevelopment of this antibiotic, to distil recommendations for future research and clinical efficacy.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Burns - Volume 39, Issue 1, February 2013, Pages 7-15
نویسندگان
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