کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
3105102 1191672 2013 5 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Evaluation of the effects of resveratrol and bevacizumab on experimental corneal alkali burn
موضوعات مرتبط
علوم پزشکی و سلامت پزشکی و دندانپزشکی مراقبت های ویژه و مراقبتهای ویژه پزشکی
پیش نمایش صفحه اول مقاله
Evaluation of the effects of resveratrol and bevacizumab on experimental corneal alkali burn
چکیده انگلیسی

PurposeTo evaluate the effects of resveratrol and bevacizumab on experimental corneal neovascularization.MethodA corneal alkali burn was performed in 62 eyes of 31 male white Vienna rabbits. Resveratrol (group 1), dimethyl sulfoxide (group 2), bevacizumab (group 3) and 0.9% NaCl (group 4) were administered to both eyes of the rabbits by subconjunctival injection for 7 days. Corneal photos were taken at 15 days after alkali injury. Inflammatory index scores and neovascularization areas were calculated.ResultsIn bevacizumab group both inflammatory index scores and the calculation of the corneal neovascularization area was significantly less than the groups.ConclusionThe subconjunctival administration of bevacizumab inhibits corneal neovascularization effectively in the rabbit corneal alkali burn model. No effect of resveratrol to the corneal neovascularization on experimental model of the corneal alkali burn was seen at the doses of usage.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Burns - Volume 39, Issue 2, March 2013, Pages 326–330
نویسندگان
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