Matriderm® versus Integra®: A comparative experimental study

AimTo compare engraftment rates and vascularisation in a rat model using either Integra Artificial Skin® or Matriderm®.MethodsMatriderm® and the dermal part of Integra® were compared in a two-step procedure including matrix implantation and subsequent epidermal grafting. Neonatal rat epidermis was used as coverage to test for rapid and complete take.ResultsEfficiency and quality of vascularisation expressed by take rate of epidermis, and thickness of resulting neodermis, were identical for both matrices.ConclusionThis first comparison of Matriderm® with Integra® in a rat model revealed no major differences in engraftment rates or vascularisation.