کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
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3132658 | 1584151 | 2013 | 6 صفحه PDF | دانلود رایگان |
![عکس صفحه اول مقاله: Effect of remifentanil on the hemodynamic responses and recovery profile of patients undergoing single jaw orthognathic surgery Effect of remifentanil on the hemodynamic responses and recovery profile of patients undergoing single jaw orthognathic surgery](/preview/png/3132658.png)
The aim of this study was to compare fentanyl-based versus remifentanil-based anesthesia with regards to the intraoperative hemodynamic stress response and recovery profiles in patients undergoing Le Fort I osteotomy. Seventeen patients were randomly divided into two groups: patients in the F-group received 2 μg/kg fentanyl intravenously followed by an infusion of 0.03–0.06 μg/kg/min, while patients in the R-group received a 0.5 μg/kg bolus of remifentanil followed by an infusion of 0.0625–0.250 μg/kg/min. Mean arterial pressure and heart rate were recorded at the following points: before anesthetic induction, at endotracheal intubation, 5 min after intubation, at incision, just before the osteotomy, during the osteotomy, during the maxillary fracturing, at suturing, at extubation, 5 min after extubation, and then 15 and 30 min postoperatively. Heart rate and mean arterial pressure were significantly lower in the R-group in comparison to the F-group from t1 to t9 (P < 0.05). All measured recovery times were significantly shorter in the R-group (P < 0.05). The incidence of postoperative side effects was comparable between groups. Remifentanil-based anesthesia is an appropriate alternative to fentanyl during Le Fort I orthognathic surgery; it promotes hemodynamic stability, blunts the stress response to noxious stimuli, and provides a better recovery profile.
Journal: International Journal of Oral and Maxillofacial Surgery - Volume 42, Issue 8, August 2013, Pages 988–993