Vector analysis of porosity evidences bone loss at the epiphysis in the BTX rat model of disuse osteoporosis

Paralysis of a unilateral quadriceps induces bone loss at the metaphysis of the long bones. However, the epiphysis, having a reduced bone remodeling is also concerned by disuse. MicroCT analysis of this part of the bones is difficult due to its complex shape in 3D. Vector analysis is a new and robust method to quantify bone loss in such complex areas.