کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
3142851 1196794 2015 4 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Tumor necrosis factor-alpha levels in the synovial fluid of patients with temporomandibular joint internal derangement
ترجمه فارسی عنوان
سطح ناکافی تومور فاکتور آلفا در مایع سینوویال بیماران مبتلا به اختلال داخلی مفصل مفصلی اندومتری
موضوعات مرتبط
علوم پزشکی و سلامت پزشکی و دندانپزشکی دندانپزشکی، جراحی دهان و پزشکی
چکیده انگلیسی

PurposeThe purpose of this study was to investigate the level of tumor necrosis factor-alpha (TNF-α) in the synovial fluid (SF) of patients with temporomandibular joint (TMJ) internal derangement and to show the relationship between the level of TNF-α and the severity of the disease.Materials and methodsArthrocentesis was performed on 32 female and five male patients (aged between 17 and 45) referred to our clinic with the complaint of TMJ pain and discomfort. TNF-α levels were determined in the SF samples obtained during arthrocentesis. As a measure of pain, visual analog scale (VAS) scores were also evaluated.ResultsThere were statistically significant differences in VAS scores between the stages. VAS scores were found to be elevated as the stage of disease progressed. Increased levels of TNF-α were found in progressive stages of internal derangement.ConclusionIn our study, both SF TNF-α levels and pain levels (VAS scores) were found to be increased in patients with internal derangement as the stage of the disease progresses. TNF-α might contribute to the pathogenesis of synovitis and the degeneration of the TMJ cartilage and bone.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Journal of Cranio-Maxillofacial Surgery - Volume 43, Issue 1, January 2015, Pages 102–105
نویسندگان
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