کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
3144078 1196845 2010 9 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Comparison of computed tomography and microradiography for graft evaluation after reconstruction of critical size bone defects using β-tricalcium phosphate
موضوعات مرتبط
علوم پزشکی و سلامت پزشکی و دندانپزشکی دندانپزشکی، جراحی دهان و پزشکی
پیش نمایش صفحه اول مقاله
Comparison of computed tomography and microradiography for graft evaluation after reconstruction of critical size bone defects using β-tricalcium phosphate
چکیده انگلیسی

SummaryIntroductionThe aim of the study was to evaluate the accuracy of computed tomography (CT) for in vivo follow up after mandibular reconstruction.Material and methodsUnilateral mandibular defects were surgically created in ten sheep and either reconstructed using blood soaked beta-tricalcium phosphate (β-TCP) cylinders (group A, n = 5) or blood soaked β-TCP cylinders that were additionally loaded with autologous bone marrow (group B, n = 5). The two graft designs resulted in different stages of graft ossification representative of different stages of healing. CT datasets were fused with microradiographs and measurements of ceramic area based on both methods were compared.ResultsTwo animals (groups A (n = 1) and B (n = 1)) presented infection and graft dislocation that was visible on CT and were excluded from statistical evaluation. Group A grafts underwent moderate degradation (53.55% ± 9.7) and incomplete bony incorporation representing an intermediate state of healing while ceramic grafts within group B developed a high grade of osseointegration and degradation (94.2% ± 3.3) consistent with progressive healing. Statistical comparison of measurements based on both methods revealed a significant bias (p < 0.05) and a non-significant variance for group A and a significant variance (p < 0.05) and non-significant bias for group B.ConclusionOur results indicate that conventional CT is not suitable to objectively evaluate ossification and degradation of a β-TCP graft in vivo and further attempts to improve clinical visualization of β-TCP need to be undertaken.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Journal of Cranio-Maxillofacial Surgery - Volume 38, Issue 1, January 2010, Pages 38–46
نویسندگان
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