کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
3146738 1197315 2014 6 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Blood Profile and Histology in Oral Infections Associated with Diabetes
ترجمه فارسی عنوان
مشخصات خون و بافت شناسی در عفونت های خوراکی مرتبط با دیابت
موضوعات مرتبط
علوم پزشکی و سلامت پزشکی و دندانپزشکی دندانپزشکی، جراحی دهان و پزشکی
چکیده انگلیسی

IntroductionWe aimed to investigate the relationship between blood profile and histologic findings in both apical periodontitis (AP) and periodontal disease (PD) associated with diabetes.MethodsWistar rats (N = 80) were assigned to the following 8 groups: control, AP, PD, AP associated with PD, diabetes, diabetes with AP, diabetes with PD, and diabetes with AP and PD. Diabetes mellitus (DM) was induced with streptozotocin, AP was induced by exposure to the oral environment, and PD was induced using periodontal ligature. After 30 days, blood samples were collected, and the rats were euthanized. Subsequently, the maxillae were processed for light microscopy. Hematologic examinations were conducted to determine the total number of erythrocytes and leukocytes, erythrocyte constant, and blood glucose level. One-way analysis of variance and Kruskal-Wallis tests were used for statistical analysis, and the significance was set at P < .05.ResultsA significant correlation was found between the histologic findings and blood parameters.ConclusionsIn conclusion, diabetes accelerated the development and progression of AP and PD in the rats and caused an increase in the average erythrocyte volume as well as the leukocyte and neutrophil counts. Oral infections increase the total number of leukocytes, the number of neutrophils and lymphocytes, and blood glucose concentrations in DM rats.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Journal of Endodontics - Volume 40, Issue 8, August 2014, Pages 1139–1144
نویسندگان
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