Matrix Metalloproteinase-2 Expression Induced by Two Different Adhesive Systems on Human Pulp Fibroblasts

HPFs display increased MMP-2 expression after 96 hours of conditioning of the HPF culture medium with polymerized disks of dentin bonding systems. This MMP-2 expression/activation may represent a defence mechanism exhibited by HPFs towards monomers eluted from the dentin bonding systems.