Efficacy of Berberine, an Antimicrobial Plant Alkaloid, as an Endodontic Irrigant against a Mixed-culture Biofilm in an In Vitro Tooth Model

Berberine was more effective than saline as an endodontic irrigant against selected endodontic pathogens in vitro and, when combined with CHX, was comparable with NaOCl in its bactericidal efficacy.