کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
3154579 1198051 2008 9 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Expression of Osteocalcin During Surgically Assisted Rapid Orthodontic Tooth Movement in Beagle Dogs
موضوعات مرتبط
علوم پزشکی و سلامت پزشکی و دندانپزشکی دندانپزشکی، جراحی دهان و پزشکی
پیش نمایش صفحه اول مقاله
Expression of Osteocalcin During Surgically Assisted Rapid Orthodontic Tooth Movement in Beagle Dogs
چکیده انگلیسی

PurposeTo investigate the expression of osteocalcin during rapid orthodontic tooth movement aided by alveolar surgery in beagle dogs.Materials and MethodsEight male beagles were used, and bilateral mandibular second premolars were extracted for distalization of the first premolars against the third premolars by orthodontic NiTi coil spring with a force of 100 gm. Right and left mandibular sides were randomly assigned to experimental and sham sides, and alveolar surgery was performed only on the experimental side to reduce the osteal resistance on the mesial side of the extraction socket. Distance of tooth movement was measured once a week during the first 4 weeks. Two beagles were sacrificed after 1, 2, 4, and 8 weeks of orthodontic force application, and expression of osteocalcin was demonstrated by immunohistochemistry and quantified with computer-aided image analysis.ResultsThe average total movement of the first premolars in 4 weeks on the experimental side (1.868 ± 0.022 mm) was approximately double that on the sham side (1.008 ± 0.057 mm). As regards the average total anchorage loss, no significant difference (P > .05) was revealed. Dynamic osteocalcin concentrations presented at 4 time periods (P < .05). The staining intensity of osteocalcin on the experimental sides was higher than the corresponding sham sides, and that on the compression sites higher than the corresponding tension sites (P < .05).ConclusionsThe results suggested that alveolar surgery might serve as an effective and safe way to accelerate orthodontic tooth movement, and promote the rate of bone remodeling as revealed by the expression of osteocalcin.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Journal of Oral and Maxillofacial Surgery - Volume 66, Issue 12, December 2008, Pages 2467–2475
نویسندگان
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