کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
3155624 1198086 2006 6 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Surgical Salvage for Local and Regional Recurrence in Oral Cancer
موضوعات مرتبط
علوم پزشکی و سلامت پزشکی و دندانپزشکی دندانپزشکی، جراحی دهان و پزشکی
پیش نمایش صفحه اول مقاله
Surgical Salvage for Local and Regional Recurrence in Oral Cancer
چکیده انگلیسی

PurposeTo evaluate local and regional recurrence and the outcomes for salvage surgery in patients for oral cancer.Patients and MethodsThis study analyzed 354 consecutive patients with oral cancer treated primarily by surgery or surgery combined with adjuvant therapy by 1 surgeon (R.A.O.) between February 1991 and September 2001.ResultsOverall recurrence rate was 15.5%; with 5.4% local, 8.5% regional, and 1.4% locoregional. Overall salvage for local recurrence was 52.6% 3-year survival, and statistically significant favorable prognostic factors were salvaged by surgery alone and initial cancer staging of I/II. Overall salvage for regional recurrence was 50%, with recurrence in a previously untreated neck and salvage with radical neck dissection plus radiotherapy giving the best prognosis. No patients with locoregional recurrence were salvaged.ConclusionsPatients who were stage I/II and were treated initially by surgery alone were the best candidates for salvage if they recurred. Salvage was best achieved with surgery or surgery + adjuvant therapy, and patients recurring within 6 months had a worse survival. Patients with locoregional recurrence or treated with RT ± chemotherapy alone have negligible survival.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Journal of Oral and Maxillofacial Surgery - Volume 64, Issue 9, September 2006, Pages 1409–1414
نویسندگان
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