Evaluation of Nuclear Morphometry and DNA Ploidy Status for Detection of Malignant and Premalignant Oral Lesions: Quantitative Cytologic Assessment and Review of Methods for Cytomorphometric Measurements

Cytomorphometric analysis via oral brush biopsy is a valuable adjunct to biopsy for identification of premalignant and early stage cancerous oral lesions as a rapid and minimally invasive procedure with high specificity and sensitivity rates, requiring no topical or local anesthetic.