Does Computed Tomographic Assessment of Inferior Alveolar Canal Cortical Integrity Predict Nerve Exposure During Third Molar Surgery?

PurposeTo evaluate the association between computed tomographic (CT) assessment of inferior alveolar nerve (IAN) canal cortical integrity and intraoperative IAN exposure.Materials and MethodsThis was a retrospective cohort study. The study sample included patients considered at high risk for IAN injury based on panoramic findings. The primary predictor variable was IAN canal integrity (intact or interrupted) assessed on coronal CT images. The secondary predictor variable was length of the cortical defect, in millimeters. The primary outcome variable was intraoperative visualization of the IAN. Other variables were demographic and operative parameters. Bivariate and multiple logistic regression analyses were used to evaluate the unadjusted and adjusted associations between the cortical integrity and IAN exposure. Diagnostic test characteristics were computed for cortical integrity and threshold cortical defect size. A P value ≤0.05 was statistically significant.ResultsThe sample consisted of 51 subjects (57% female) with a mean age of 35.2 ± 12.8 years. Of the 80 third molars available for evaluation, 52 third molars (64.1%) had evidence of loss of cortical integrity. The mean cortical defect length was 2.9 ± 2.6 mm. Loss of cortical integrity had a high sensitivity (≥0.88) but low specificity (≤0.49) as a diagnostic test for IAN visualization. A cortical defect size ≥3 mm was associated with an increased risk for intraoperative IAN visualization with a high sensitivity and specificity (≥0.82).ConclusionCortical defect size on a maxillofacial CT has a high sensitivity and specificity for predicting intraoperative IAN exposure during third molar removal.