Maxillofacial and Axial/Appendicular Giant Cell Lesions: Unique Tumors or Variants of the Same Disease?-A Comparison of Phenotypic, Clinical, and Radiographic Characteristics

These results suggest that MF and AA GCLs represent a similar, if not the same, disease. Comparing the aggressive and nonaggressive subgroups, more similarities were found than when evaluating without stratification by clinical behavior. The remaining differences could be explained by the likelihood that MF tumors are diagnosed earlier than AA tumors because of facial exposure and dental screening examinations and radiographs.