Effects of Platelet-Rich Plasma on the Healing of Autologous Bone Grafted Mandibular Defects in Dogs

PRP appeared to enhance early autologous graft healing. However, after 2 months this effect is no longer significant. The early enhanced healing occurred by increasing the amount of non-viable grafted bone that was removed and increasing the amount of new bone that was formed. PRP did not change the rate at which new bone was formed, and no increase in trabecular density was realized in these grafts.