کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
3162493 1198632 2008 4 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Effects of Low Dose Vasopressin in Catecholamine Resistant Septic Shock
موضوعات مرتبط
علوم پزشکی و سلامت پزشکی و دندانپزشکی دندانپزشکی، جراحی دهان و پزشکی
پیش نمایش صفحه اول مقاله
Effects of Low Dose Vasopressin in Catecholamine Resistant Septic Shock
چکیده انگلیسی

BackgroundSeptic shock commonly leads to death in critically ill patients. Severe hypotension resistant to conventional catecholamine leads to multiorgan failure. We studied the effectiveness of low dose vasopressin in resistant septic shock.MethodsThirty critically ill patients with catecholamine resistant hypotension were included in the study. After adequate fluid resuscitation, infusion of norepinephrine and dobutamine was started. If the patient remained hypotensive, vasopressin was infused at a fixed rate of 0.04 unit/minute for 24 hours. Haemodynamic parameters and mortality rates were recorded.ResultThere was a significant improvement in systolic and mean arterial pressure within four hours of starting vasopressin. This improvement continued throughout the 24-hour period. In addition, it was possible to withdraw dopamine in all the patients and significantly reduce infusion rates of dobutamine and norepinephrine. No significant complication was noted.ConclusionLow dose vasopressin at the rate of 0.04 unit/minute is an effective vasopressor in adult patients with catecholamine resistant septic shock.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Medical Journal Armed Forces India - Volume 64, Issue 4, October 2008, Pages 304–307
نویسندگان
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