کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
3174883 1200105 2016 5 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Granulome central à cellules géantes de l'enfant : présentation des différentes options thérapeutiques
موضوعات مرتبط
علوم پزشکی و سلامت پزشکی و دندانپزشکی دندانپزشکی، جراحی دهان و پزشکی
پیش نمایش صفحه اول مقاله
Granulome central à cellules géantes de l'enfant : présentation des différentes options thérapeutiques
چکیده انگلیسی
Central giant cell granuloma (CGCG) is a benign tumor that may be subdivided in a non-aggressive form and an aggressive form. In aggressive forms, tumor size and high recurrence risk need large surgical resections. In order to minimize surgical morbidity, especially in children, medical treatments acting on the tumor proliferation are currently being assessed: steroids (triamcinolone), anti-osteoclastic drugs (calcitonine, alendronate, denosumab), anti-angiogenic drugs (interferon α). However to date, there is no evidence for any superiority of medical over surgical treatment. Complete response is rarely obtained and additional surgery is often necessary to remove the tumor in case of tumor progression, to remove a remnant or to remodel bone. Moreover, these drugs have frequent local or systemic side effects such as osteonecrosis and growth deficiencies.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Revue de Stomatologie, de Chirurgie Maxillo-faciale et de Chirurgie Orale - Volume 117, Issue 3, June 2016, Pages 142-146
نویسندگان
, , , , ,