کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
3178671 1200399 2014 7 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
The current status of preoperative biliary drainage for patients who receive pancreaticoduodenectomy for periampullary carcinoma: A comprehensive review
ترجمه فارسی عنوان
وضعیت فعلی تخلیه صفراوی قبل از عمل جراحی برای بیماران مبتلا به پانکراتیاودوژنکتومی برای کارسینوم پری آمپولار: بررسی جامع
موضوعات مرتبط
علوم پزشکی و سلامت پزشکی و دندانپزشکی دندانپزشکی، جراحی دهان و پزشکی
چکیده انگلیسی

BackgroundSurgery on patients with malignant obstructive jaundice carries increased risks of postoperative morbidity and mortality. Preoperative biliary drainage has been developed to reduce this procedure-related risks, but its role in patients who are going to receive pancreaticoduodenectomy for periampullary carcinoma is still controversial.MethodsThis article aimed at reviewing the current status of preoperative biliary drainage for patients with peri-ampullary tumors who were candidates for pancreaticoduodenectomy. A MEDLINE and PubMed database search from 1980 to 2013 was performed to identify relevant articles using the keywords “pancreaticoduodenectomy”, “preoperative biliary drainage”, “jaundice”, “peri-ampullary neoplasm” and “carcinoma of pancreas”. Additional papers were identified by a manual search of the references from the key articles.ResultsThere were six randomized controlled trials (RCTs) and 5 meta-analyses on preoperative biliary drainage for patients with malignant obstructive jaundice. Most of the results of these studies could not be used to define the role of preoperative biliary drainage for patients who received pancreaticoduodenectomy for periampullary carcinoma because: first, the majority of these studies were on bypass or palliative resections; second, various pathologies with both proximal and distal biliary obstruction were included; third, there were different forms of percutaneous or endoscopic drainage procedures; fourth, there were different durations of preoperative drainage; and finally, there were variations in the definition of events and outcomes. There was only one RCT which included a homogeneous group of patients with carcinoma of pancreas who underwent pancreaticoduodenectomy. For patients with periampullary tumor, the RCTS and meta-analyses showed no benefit of preoperative biliary drainage. Instead, there were some concerns about the drainage-related complications and the increase in positive intraoperative bile culture rate and the associated infective complication rate postoperatively.ConclusionRoutine preoperative biliary drainage showed no beneficial effect on the surgical outcome for patients with periampullary tumor. A selective approach of preoperative biliary drainage should be adopted for these patients. The optimal duration and modality of preoperative biliary drainage remain unclear.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: The Surgeon - Volume 12, Issue 5, October 2014, Pages 290–296
نویسندگان
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