Post-transplant lymphoproliferative disease

Post-transplant lymphoproliferative disorder/disease (PTLD) is a B-cell proliferation disorder following infection with Epstein–Barr virus due to therapeutic immunosuppression after organ transplantation. The more intense the immunosuppression, the higher the incidence of PTLD and the earlier it occurs. The cornerstone of successful treatment of PTLD is reduction or withdrawal of immunosuppression.