کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
3239293 1205995 2015 6 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
A retrospective study of antibiotic prophylaxis value in surgical treatment of lower limb fracture
ترجمه فارسی عنوان
یک مطالعه گذشته نگری ارزش پیشگیری از آنتی بیوتیک در درمان جراحی شکستگی اندام تحتانی
موضوعات مرتبط
علوم پزشکی و سلامت پزشکی و دندانپزشکی طب اورژانس
چکیده انگلیسی

BackgroundSurgical site infections (SSI) are nosocomial infections that cause considerable problems in orthopaedic surgery. Antibiotic prophylaxis can be used to reduce the risk for SSI. There is no universal antibiotic that can be recommended for prophylaxis in terms of coverage of all possible pathogens because of antibiotic resistance, and there are no universal recommendations for different types of patients in terms of injury type, selected operation and risk factors for development of SSI. The aim of this study was to analyse the effectiveness of antibiotic prophylaxis in surgical treatment (ORIF) of closed lower limb fractures in young, healthy patients.Patients and methodsPatient details were collected from the patient histories. Inclusion criteria for participants were age 20–30 years, not suffering from any type of chronic disease or state that may affect postoperative infection and ISS ≤ 9. Antibiotic prophylaxis use and outcome (SSI) were compared between two groups of patients. Data were analysed using descriptive statistics, Fisher's exact test and t-test for proportions.ResultsA total of 347 patients with closed lower limb fractures treated with ORIF met the inclusion criteria. There were 290 male and 57 female patients, with an average age of 24.47 years. Prophylactic antibiotics were given to 242 patients (69.74%); 2 g ceftriaxone was administered to 88.02% of the patients who received antibiotic prophylaxis. Ten patients developed postoperative infection (eight out of 242 with antibiotic prophylaxis and two out of 105 without antibiotic prophylaxis). The difference between the two groups was not statistically significant (Fisher's exact test, P = 0.749).ConclusionAntibiotic prophylaxis was ineffective in preventing SSI in patients with no risk factors for SSI who were undergoing ORIF for closed lower limb fractures.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Injury - Volume 46, Supplement 6, November 2015, Pages S67–S72
نویسندگان
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