کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
3242816 1206130 2008 7 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Randomised controlled trials in orthopaedic surgery and traumatology: Overview of parameters and pitfalls
موضوعات مرتبط
علوم پزشکی و سلامت پزشکی و دندانپزشکی طب اورژانس
پیش نمایش صفحه اول مقاله
Randomised controlled trials in orthopaedic surgery and traumatology: Overview of parameters and pitfalls
چکیده انگلیسی

SummaryThere is a growing consensus that randomised controlled clinical trial (RCT) provide a secure basis for determining treatment effects. Prospective randomised clinical trials can be a powerful tool in medical science and evidence-based medicine. A well-defined study hypothesis, with a prospectively applied study design, blinded and randomised treatment allocation and assessment, with appropriate control groups can provide strong evidence in support of treatment decisions. However, the recent reviews of the medical literature indicate that the study design itself does not ensure the quality of science or useful and valid scientific data. Thus, regardless of the study design or level of evidence, it remains imperative for the physician and surgeon to critically evaluate a scientific report. Moreover, as randomisation, concealment of treatment allocation and blinding are difficult issues to resolve in orthopaedic surgery, future trials should focus on detailed and correct reporting of outcome measures.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Injury - Volume 39, Issue 6, June 2008, Pages 636–642
نویسندگان
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