کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
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3243133 | 1206153 | 2007 | 6 صفحه PDF | دانلود رایگان |
![عکس صفحه اول مقاله: The effect of the timing of antibiotics and surgical treatment on infection rates in open long-bone fractures: A 9-year prospective study from a district general hospital The effect of the timing of antibiotics and surgical treatment on infection rates in open long-bone fractures: A 9-year prospective study from a district general hospital](/preview/png/3243133.png)
SummaryAimsTo determine whether a delay of greater than 6 h from injury to initial surgical debridement and the timing of antibiotic administration affect infection rates in open long-bone fractures.MethodsWe studied 248 consecutive open long-bone fractures in 237 patients over a 9-year period. The patients were followed until clinical or radiological union occurred or until a secondary procedure for non-union or infection was performed.ResultsSurgical debridement was performed within 6 h of injury in 62% of cases and after 6 h in 38% of cases. Infection rates were 7.8% and 9.6%, respectively, and the difference was not statistically significant (p = 0.6438). The timing of antibiotic administration was not significantly related to the infection rate.ConclusionWhilst open long-bone fractures should be treated expeditiously, we suggest that adherence to a 6 h window has not been shown to affect infection rates nor has the timing of antibiotic administration during the acute phase.
Journal: Injury - Volume 38, Issue 8, August 2007, Pages 900–905