کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
325963 1433020 2008 16 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Effect of Stimulants on Height and Weight: A Review of the Literature
موضوعات مرتبط
علوم پزشکی و سلامت پزشکی و دندانپزشکی پریناتولوژی (پزشکی مادر و جنین)، طب اطفال و بهداشت کودک
پیش نمایش صفحه اول مقاله
Effect of Stimulants on Height and Weight: A Review of the Literature
چکیده انگلیسی

ObjectiveStimulant medications are effective treatments for attention-deficit/hyperactivity disorder, but concerns remain about their effects on growth.MethodWe provide a quantitative analysis of longitudinal studies about deficits in expected growth among children with attention-deficit/hyperactivity disorder treated with stimulant medication. Study selection criteria were use of DSM criteria or clear operational definitions for hyperactivity or minimal brain dysfunction; outcome measures including raw, standardized, or percentile measurement of change in height and/or weight; first assessment of effects on growth occurred during childhood; and follow-up for at least 1 year. For issues not suitable for quantitative analyses, we provide a systematic, qualitative review.ResultsThe quantitative analyses showed that treatment with stimulant medication led to statistically significant delays in height and weight. This review found statistically significant evidence of attenuation of these deficits over time. The qualitative review suggested that growth deficits may be dose dependent, deficits may not differ between methylphenidate and amphetamine, treatment cessation may lead to normalization of growth, and further research should assess the idea that attention-deficit/hyperactivity disorder itself may be associated with dysregulated growth.ConclusionsTreatment with stimulants in childhood modestly reduced expected height and weight. Although these effects attenuate over time and some data suggest that ultimate adult growth parameters are not affected, more work is needed to clarify the effects of continuous treatment from childhood to adulthood. Although physicians should monitor height, deficits in height and weight do not appear to be a clinical concern for most children treated with stimulants. J. Am. Acad. Child Adolesc. Psychiatry, 2008; 47(9):000–000.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Journal of the American Academy of Child & Adolescent Psychiatry - Volume 47, Issue 9, September 2008, Pages 994–1009
نویسندگان
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