کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
3262994 1207749 2011 5 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Predictors of survival in patients with malignant gastric outlet obstruction: A patient-oriented decision approach for palliative treatment
موضوعات مرتبط
علوم پزشکی و سلامت پزشکی و دندانپزشکی غدد درون ریز، دیابت و متابولیسم
پیش نمایش صفحه اول مقاله
Predictors of survival in patients with malignant gastric outlet obstruction: A patient-oriented decision approach for palliative treatment
چکیده انگلیسی

BackgroundGastrojejunostomy and stentplacement are the most commonly used treatments for malignant gastric outlet obstruction (GOO). The preference for either treatment largely depends on the expected survival. Our objective was to investigate predictors of survival in patients with malignant GOO and to develop a model that could aid in the decision for either gastrojejunostomy or stentplacement.MethodsPrognostic factors for survival were collected from a literature search and evaluated in our patient population, which included 95 retrospectively and 56 prospectively followed cases. All 151 patients were treated with gastrojejunostomy or stentplacement.ResultsA higher WHO performance score was the only significant prognostic factor for survival in our multivariable analysis (HR 2.2 95%CI 1.7–2.9), whereas treatment for obstructive jaundice, gender, age, metastases, weight loss, level of obstruction and pancreatic cancer were not. A prognostic model that includes the WHO score was able to distinguish patients with a poor survival (WHO score 3–4, median survival: 31 days) from those with a relatively intermediate or good survival (WHO score 2, median survival: 69 and WHO score 0–1, median survival: 139 days, respectively).ConclusionsOnly the WHO score is a significant predictor of survival in patients with malignant GOO. A simple prognostic model is able to guide the palliative treatment decision for either gastrojejunostomy (WHO score 0–1) or stentplacement (WHO 3–4) in patients with malignant GOO.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Digestive and Liver Disease - Volume 43, Issue 7, July 2011, Pages 548–552
نویسندگان
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