Profil des médecins prescripteurs des agonistes du récepteur du GLP-1 ou des inhibiteurs de la DPP4

Many recommendations on antidiabetic treatments for type 2 diabetes are available. GLP-1 receptor agonists and DPP-4 inhibitors are now part of our therapeutic arsenal, but their prescription remains limited. In this context, we decided to conduct a study on the profile of the physicians prescribing these drugs in the French Auvergne region regarding the medical demography, their mode of exercise, or their training. The data are obtained by individualized telephone questionnaire and from the files of the national health insurance fund (Cnamts) for a period of one year. The target population is defined by the 1077 GPs practicing in one of the four departments of the Auvergne region as listed in the directory. Data for 546 GP's have been collected. The average age of included physicians is 52.7 years. The population is made up of 178 women and 368 men. Comparing the group of prescribers of GLP-1 receptor agonists and DPP-4 inhibitors (“incretins”) to non-prescribers (health insurance data): age, practicing in a rural or urban area, group practice or medical house, and adherence to diabetes network or participation in CME on diabetes, have no influence over the choice of treatments. Prescribers of “incretins” are predominantly male, and perform more consultations and are more willing to receive pharmaceutical companies. These results are statistically significant. The choice of a medical prescription is a complex process and is discussed. However the influence of the pharmaceutical industry in the «innovative» molecules' prescribing is confirmed.