Pharmacogénétique des antidiabétiques

While there has been progress in understanding how genetic variation predisposes to diabetes, there is less of understanding of how genetics influences the drug response. Pharmacogenetics research provides a means to better understand pharmacotherapy. Preliminary results of pharmacogenetics in type 2 diabetes have identified variants that are potentially associated with differential response to antidiabetic drugs. This new area of research needs larger and well-designed genetic studies in order to develop pharmalocogical genetic screening in type 2 diabetic patients, a tool for the development of personalized pharmacotherapy.