کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
3276741 1208588 2011 8 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Antioxidant activity and hepatoprotective effects of whey protein and Spirulina in rats
موضوعات مرتبط
علوم پزشکی و سلامت پزشکی و دندانپزشکی غدد درون ریز، دیابت و متابولیسم
پیش نمایش صفحه اول مقاله
Antioxidant activity and hepatoprotective effects of whey protein and Spirulina in rats
چکیده انگلیسی

ObjectivesThe aims of the present study were to evaluate the antioxidant, radical scavenging, and metal-chelating activity of whey protein concentrate (WPC) and Spirulina alone or in combination in vitro and to evaluate their hepatoprotective effects against CCl4 in vivo.MethodsFive concentrations (20, 40, 60, 80, and 100 mg/100 mL) of WPC, Spirulina, and their combination were tested in vitro. In the in vivo study, eight groups of male rats comprised the control group and the groups treated with WPC, Spirulina alone, or in combination with or without CCl4 were used.ResultsThe in vitro study showed that WPC and Spirulina showed antioxidant, radical scavenging, and metal-chelating activities in dose-dependent manner. The in vivo study showed that both agents succeeded in preventing liver damage induced by CCl4. This prevention was more pronounced in rats receiving the combination of WPC and Spirulina.ConclusionWhey protein concentrate and Spirulina have free radical scavenging properties and antioxidant activity.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Nutrition - Volume 27, Issue 5, May 2011, Pages 582–589
نویسندگان
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