Bone Marrow Stromal Cell Transplants Prevent Experimental Enterocolitis and Require Host CD11b+ Splenocytes

MSC transplants, delivered by specific parameters, reduce colitis in mice. Interactions between MSC and CD11b+ regulatory T cells might be used to develop potency assays for MSCs, to identify nonresponders to MSC therapy, and to create new cell grafts that are composed of CD11b+ cells preconditioned by MSCs.