کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
330331 1433638 2009 5 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Accelerated aging of the putamen in men but not in women
موضوعات مرتبط
علوم زیستی و بیوفناوری بیوشیمی، ژنتیک و زیست شناسی مولکولی سالمندی
پیش نمایش صفحه اول مقاله
Accelerated aging of the putamen in men but not in women
چکیده انگلیسی

Age-related structural brain changes have been demonstrated repeatedly but data on the effect of gender on age-related structural brain changes are conflicting. Using high-resolution T1-weighted magnetic resonance imaging and voxel-based morphometry, we examined a population of 133 healthy adults (women, 73; men, 60; age range, 29–80 years) focusing on differential aging between men and women (i.e., interaction of age and gender). Compared to women, men showed accelerated age-related gray matter (GM) loss in the posterior putamen. Our data may constitute the structural substrate for age-related differences in motor function between men and women such as the higher incidence and earlier onset of Parkinson's disease in men.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Neurobiology of Aging - Volume 30, Issue 1, January 2009, Pages 147–151
نویسندگان
, , , , , , , ,