The role of CD19+CD24highCD38high and CD19+CD24highCD27+ regulatory B cells in patients with type 1 autoimmune pancreatitis

Our data suggested that CD19+CD24highCD38high Bregs seemed to increase reactively to suppress the disease activity, and are consistent with the hypothesis that CD19+CD24highCD27+ Bregs might be involved in the development of type 1 AIP, although it still remains unclear whether the decrease of CD19+CD24highCD27+ cells is cause or effect of AIP.