کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
3322664 1211822 2010 13 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Histopathology of Barrett's esophagus: A review for the practicing gastroenterologist
موضوعات مرتبط
علوم پزشکی و سلامت پزشکی و دندانپزشکی بیماری‌های گوارشی
پیش نمایش صفحه اول مقاله
Histopathology of Barrett's esophagus: A review for the practicing gastroenterologist
چکیده انگلیسی

Barrett's esophagus (BE) is the replacement of the normal squamous lining of the distal esophagus by columnar mucosa. It is the recognized precursor of esophageal adenocarcinoma, with tumors arising through an inflammation–metaplasia–dysplasia–carcinoma sequence. Effective communication between the gastroenterologist and pathologist is crucial to the diagnosis, risk assessment, and management of BE. This review will focus on the histopathologic aspects of BE especially relevant to the practicing gastroenterologist, including discussion of normal anatomy and histology of the distal esophagus and gastroesophageal junction, varying definitions of BE used around the world, histology of nondysplastic BE, significance of goblet cells, grading of Barrett neoplasia, natural history of BE, biomarkers of progression, and pathology of postablation BE and endoscopic mucosal resection.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Techniques in Gastrointestinal Endoscopy - Volume 12, Issue 2, April 2010, Pages 69–81
نویسندگان
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