Tissue Adhesives: A Review

Tissue adhesives represent a group of natural and artificial compounds that are currently used for a variety of local applications including hemostasis, wound closure, and fistula repair. The most commonly utilized tissue adhesives in GI endoscopy include cyanoacrylates, fibrin glues, and thrombin. Other adhesives, such as collagen-based sealants and PEG polymers, are beginning to be studied in various surgical disciplines and may one day find a role in endoscopic practice as well. This review covers the endoscopic use of available tissue adhesives and highlights pertinent technical considerations.