کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
3339438 1213908 2013 7 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Chronic Hepatitis E Virus Infection and Treatment
موضوعات مرتبط
علوم پزشکی و سلامت پزشکی و دندانپزشکی کبدشناسی
پیش نمایش صفحه اول مقاله
Chronic Hepatitis E Virus Infection and Treatment
چکیده انگلیسی

It is now well accepted that hepatitis E virus (HEV) infection can induce chronic hepatitis and cirrhosis in immunosuppressed patients. Chronic genotype-3 HEV infections were first reported in patients with a solid-organ transplant. Thereafter, cases of chronic HEV infection have been reported in patients with hematological disease and in those who are human immunodeficiency virus (HIV)-positive. HEV-associated extra-hepatic manifestations, including neurological symptoms, kidney injuries, and hematological disorders, have been also reported. In transplant patients, reducing the dosage of immunosuppressive drugs allows the virus to be cleared in some patients. In the remaining patients, as well as hematological patients and patients who are HIV-positive, anti-viral therapies, such as pegylated interferon and ribavirin, have been found to be efficient in eradicating HEV infection. This review summarizes our current knowledge of chronic HEV infection, its treatment, and the extra-hepatic manifestations induced by HEV.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Journal of Clinical and Experimental Hepatology - Volume 3, Issue 2, June 2013, Pages 134–140
نویسندگان
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