کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
3340696 1214068 2015 6 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Prostanoids in allergy
ترجمه فارسی عنوان
پروانستوئید در آلرژی
موضوعات مرتبط
علوم پزشکی و سلامت پزشکی و دندانپزشکی ایمونولوژی، آلرژی و روماتولوژی
چکیده انگلیسی

Prostanoids, which include prostaglandin and thromboxane, are metabolites of arachidonic acid released in various pathophysiological conditions. They induce a range of actions mediated through their respective receptors expressed on target cells. It has been demonstrated that each prostanoid receptor has multiple functions and that the effect of receptor stimulation can vary depending on context; this sometimes results in opposing effects, such as simultaneous excitatory and inhibitory outcomes. The balance between the production of each prostanoid and the expression of its receptors has been shown to be important for maintaining homeostasis but also involved in the development of various pathological conditions such as allergy. Here, we review the recent findings on the roles of prostanoids in allergy, especially focusing on atopic dermatitis and asthma.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Allergology International - Volume 64, Issue 1, January 2015, Pages 11–16
نویسندگان
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