کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
3343551 1214430 2006 17 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Nutraceuticals: do they work and when should we use them?
موضوعات مرتبط
علوم پزشکی و سلامت پزشکی و دندانپزشکی ایمونولوژی، آلرژی و روماتولوژی
پیش نمایش صفحه اول مقاله
Nutraceuticals: do they work and when should we use them?
چکیده انگلیسی

There are numerous biological mechanisms by which nutritional factors might be expected to exert favorable influences on pathophysiological processes in osteoarthritis. Such processes include oxidative damage, cartilage matrix degradation and repair, and chondrocyte function and responses in adjacent bone. Micronutrients for which preliminary evidence of benefit exists include vitamin C and vitamin D. In addition, numerous nutraceuticals that may influence osteoarthritis pathophysiology—including glucosamine, chondroitin, S-adenosylmethionine, ginger and avocado/soybean unsaponifiables—have been tested in clinical trials. These products are safe and well tolerated, but interpretation of the collective results is hampered by heterogeneity of the studies, inconsistent results, and the conundrum of how to reconcile an apparent structural benefit with absence or modest effect on symptoms.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Best Practice & Research Clinical Rheumatology - Volume 20, Issue 1, February 2006, Pages 99–115
نویسندگان
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