کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
3346754 1407783 2016 5 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Performance of self-collected penile-meatal swabs compared to clinician-collected urethral swabs for the detection of Chlamydia trachomatis, Neisseria gonorrhoeae, Trichomonas vaginalis, and Mycoplasma genitalium by nucleic acid amplification assays
موضوعات مرتبط
علوم زیستی و بیوفناوری ایمنی شناسی و میکروب شناسی میکروبیولوژی و بیوتکنولوژی کاربردی
پیش نمایش صفحه اول مقاله
Performance of self-collected penile-meatal swabs compared to clinician-collected urethral swabs for the detection of Chlamydia trachomatis, Neisseria gonorrhoeae, Trichomonas vaginalis, and Mycoplasma genitalium by nucleic acid amplification assays
چکیده انگلیسی


• We show that penile-meatal swabs appear to be an acceptable sample type.
• Compared to urethral swabs, penile-meatal swabs performed well.
• Men are willing to collect their own swab sample and find it easy to perform.

Men were enrolled in a study to assess the performance and acceptability of self-collected penile meatal swabs as compared to clinician-collected urethral swabs for sexually transmitted infections (STIs). We expected penile-meatal swabs to perform favorably to urethral swabs for Chlamydia trachomatis (CT), Neisseria gonorrhoeae (NG), Trichomonas vaginalis (TV), and Mycoplasma genitalium (MG) detection by nucleic acid amplification assays (NAATs). Of 203 swab pairs tested; for CT, penile-meatal swab sensitivity was 96.8% and specificity was 98.8%. NG sensitivity and specificity were 100% and 98.9%, respectively. For TV, sensitivity was 85.0% and specificity was 96.7%. For MG sensitivity and specificity were 79.3% and 99.4%, respectively. No significant statistical differences between sample type accuracy (CT: P = 0.625; NG: P = 0.248; TV: P = 0.344; and MG: P = 0.070) existed. Most men, 90.1%, reported self-collection of penile-meatal swabs as “Very Easy” or “Easy”. Self-collected penile-meatal swabs appeared acceptable for NAAT STI detection and an acceptable collection method by men.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Diagnostic Microbiology and Infectious Disease - Volume 86, Issue 2, October 2016, Pages 131–135
نویسندگان
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