کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
3346927 | 1215921 | 2015 | 5 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Analytical performance of the automated multianalyte point-of-care mariPOC® for the detection of respiratory viruses
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کلمات کلیدی
موضوعات مرتبط
علوم زیستی و بیوفناوری
ایمنی شناسی و میکروب شناسی
میکروبیولوژی و بیوتکنولوژی کاربردی
پیش نمایش صفحه اول مقاله
![عکس صفحه اول مقاله: Analytical performance of the automated multianalyte point-of-care mariPOC® for the detection of respiratory viruses Analytical performance of the automated multianalyte point-of-care mariPOC® for the detection of respiratory viruses](/preview/png/3346927.png)
چکیده انگلیسی
The analytical performance of mariPOC® respi test (ArcDia® Laboratories, Turku, Finland) was evaluated using nucleic acid amplification techniques (NAATs) as the gold standard. The mariPOC assay allows automated detection of antigens from 8 respiratory viruses: influenza A and B viruses, respiratory syncytial virus, adenovirus, human metapneumovirus, and parainfluenza viruses 1-3. Positive results from samples with high viral load are available in 20 min. Nasopharyngeal aspirates (n = 192) from patients with acute respiratory infection and from previously positive samples were analyzed by mariPOC and NAATs (SimplexaTM FluA/FluB & RSV kit [n = 118] and Luminex® Respiratory virus panel xTAG® RVP FAST [n = 74]). Sensitivity, specificity, positive predictive value, and negative predictive value of mariPOC were 85.4%, 99.2%, 95.9%, and 97%, respectively, and 84.6% of positive results were reported in 20 min. The good analytical performance and extended portfolio of mariPOC show this rapid assay as a good alternative for the etiological diagnosis of acute respiratory infection in laboratories that are not equipped with molecular assays.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Diagnostic Microbiology and Infectious Disease - Volume 83, Issue 3, November 2015, Pages 252-256
Journal: Diagnostic Microbiology and Infectious Disease - Volume 83, Issue 3, November 2015, Pages 252-256
نویسندگان
Sara Sanbonmatsu-Gámez, Mercedes Pérez-Ruiz, Ana Lara-Oya, Irene Pedrosa-Corral, Cristina Riazzo-Damas, José MarÃa Navarro-MarÃ,