کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
3348059 1215996 2010 5 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
High prevalence of extended-spectrum β-lactamases and plasmid-mediated AmpC β-lactamases in Enterobacteriaceae isolated from long-term care facilities in Korea
موضوعات مرتبط
علوم زیستی و بیوفناوری ایمنی شناسی و میکروب شناسی میکروبیولوژی و بیوتکنولوژی کاربردی
پیش نمایش صفحه اول مقاله
High prevalence of extended-spectrum β-lactamases and plasmid-mediated AmpC β-lactamases in Enterobacteriaceae isolated from long-term care facilities in Korea
چکیده انگلیسی

The aim of this study was to investigate for the first time the prevalence and types of extended-spectrum β-lactamase (ESBL) and plasmid-mediated AmpC β-lactamase (PABL) in Enterobacteriaceae in Korean long-term care facilities (LTCFs). ESBL rates were 45.3% (72/159) in Escherichia coli and 42.7% (50/117) in Klebsiella pneumoniae. In E. coli, CTX-M-28, the most prevalent ESBLs, was identified for the first time in Korea in 44 isolates. In K. pneumoniae, SHV-12 was found in 27 isolates (52.9% of ESBLs), among which 25 isolates also contained SHV-11. Twenty-seven isolates had SHV and CTX-M β-lactamase simultaneously. PABL genes were detected in 39.3% (46/117) of K. pneumoniae and 3.1% (5/159) E. coli. In E. coli, DHA-1(3), CMY-2(1), and CMY-6(1) were detected, whereas in K. pneumoniae, only DHA-1 was detected. Among the PABL-producing organisms, 80.0% (E. coli) and 52.2% (K. pneumoniae) simultaneously produced ESBLs. In conclusion, LTCF residents in Korea have a very high prevalence of E. coli and K. pneumoniae producing ESBLs, PABLs, or both, and the genotypes of ESBL and PABL were identical with those found in general hospitals.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Diagnostic Microbiology and Infectious Disease - Volume 67, Issue 3, July 2010, Pages 261–265
نویسندگان
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