کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
335201 546817 2008 10 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Auditory sensory gating to the human voice: A preliminary MEG study
موضوعات مرتبط
علوم زیستی و بیوفناوری علم عصب شناسی روانپزشکی بیولوژیکی
پیش نمایش صفحه اول مقاله
Auditory sensory gating to the human voice: A preliminary MEG study
چکیده انگلیسی

The ability of the brain to suppress incoming irrelevant sensory input is termed ‘sensory gating,' and auditory sensory gating is often indexed by the auditory evoked response. We recorded the auditory evoked magnetic fields to the human voice, using the conditioning–testing paradigm, to investigate whether or not healthy subjects show less activation to the second voice stimulus. Seventeen healthy adults (mean age 27.9 ± 4.8 years, 9 males and 8 females) participated in the experiment. The auditory stimuli were presented monaurally as a series of 120 paired voices, with 500-ms interstimulus intervals and 6-s interpaired stimulus intervals. The P50m and the N100m responses were investigated, and dipole source localization was performed. Root mean squares of both P50m and N100m were significantly suppressed to the second stimulus bilaterally, and the suppression was more significant in N100m. The N100m was located significantly more laterally than the P50m for both hemispheres. These results therefore demonstrate the presence of sensory gating for auditory inputs of the human voice in the primary auditory cortex and the auditory association area.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Psychiatry Research: Neuroimaging - Volume 163, Issue 3, 30 August 2008, Pages 260–269
نویسندگان
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