کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
3352392 | 1216479 | 2007 | 5 صفحه PDF | دانلود رایگان |
![عکس صفحه اول مقاله: Application of Human Leukocyte Antigen–G Expression in the Diagnosis of Human Cancer Application of Human Leukocyte Antigen–G Expression in the Diagnosis of Human Cancer](/preview/png/3352392.png)
It has been well known that human leukocyte antigen (HLA)–G molecules are present in a variety of human neoplastic diseases, and the molecule may contribute to the escape of tumor cells from immune surveillance. Besides the studies that aim at elucidating the roles of HLA-G in immune regulation, the researches that focus on potential applications of HLA-G expression in cancer diagnosis represent another perspective in HLA-G research. This review summarizes those recent translational studies of HLA-G expression in the diagnosis of human cancer. Specifically, the promises and challenges for applying HLA-G expression to detect cancer in body fluids, to diagnose different types of human cancer and to predict clinical outcome in cancer patients will be briefly reviewed.
Journal: Human Immunology - Volume 68, Issue 4, April 2007, Pages 272–276